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Product Information:

Rocaglamide

Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM.

Cat. No.: EX-A3220    Purity: >98%
Rocaglamide
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg1085In-stock
50mg1885In-stock
100mg2985In-stock
200mgGet quoteIn-stock
500mgGet quoteIn-stock
1gGet quoteinquire


SynonymsRocaglamide A
Synonyms 2Roc-A
CAS No.84573-16-0
Purity>98%
FormulaC29H31NO7
Mol Weight505.5589
Appearancewhite to off-white powder
SolubilityDMSO>50mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Santagata S, et al. Tight coordination of protein translation and heat shock factor 1 activation supports the anabolic malignant state. Science. 2013 Jul 19; 341(6143): 1238303.

[2]. Baumann B, et al. Rocaglamide derivatives are potent inhibitors of NF-kappa B activation in T-cells. J Biol Chem. 2002 Nov 22;277(47):44791-800.
CoACoA of Rocaglamide
Smiles:O1C2=CC(OC)=CC(OC)=C2[C@]2(O)[C@H](O)[C@H](C(N(C)C)=O)[C@@H](C3=CC=CC=C3)[C@]12C1=CC=C(OC)C=C1

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