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Product Information:

JNJ1661010

JNJ-1661010 (Takeda-25) a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with IC50s of 34 and 33 nM for rat FAAH and human FAAH, respectively. JNJ-1661010 can cross the blood-brain barrier and used as broad-spectrum analgesics.

Cat. No.: EX-A2218    Purity: >98%
JNJ1661010
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg1385In-stock
1g2085In-stock


SynonymsTakeda-25
CAS No.681136-29-8
Purity>98%
FormulaC19H19N5OS
Mol Weight365.452
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Keith JM, et al. Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4838-43.

[2]. Karbarz MJ, et al. Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylicacid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. Anesth Analg. 2009 Jan;108(1):316-29.

CoACoA of JNJ1661010
Smiles:O=C(NC1=CC=CC=C1)N1CCN(CC1)C1=NC(=NS1)C1=CC=CC=C1

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