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Product Information:

LY2090314

LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 values of 1.5 nM and 0.9 nM for GSK-3α and GSK-3β, respectively.

Cat. No.: EX-A2214    Purity: >98%
LY2090314
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg750In-stock
500mg985In-stock
1g1485In-stock
5g4150In-stock
10g6550In-stock


CAS No.603288-22-8
Purity>98%
FormulaC28H25FN6O3
Mol Weight512.5349
AppearanceOff-white to orange solid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zamek-Gliszczynski MJ, et al. Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure. Dr

[2]. Atkinson JM, et al. Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma--Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3. PLoS One. 2015 Apr 27;10(4):e0125028.

CoACoA of LY2090314
Smiles:FC1=CC2=C3N(CCN(CC3=C1)C(=O)N1CCCCC1)C=C2C1=C(C(=O)NC1=O)C1=CN=C2C=CC=CN12

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