Product Information:
Cat. No.: EX-A2172 | Purity: >98% |
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CAS No. | 537049-40-4 |
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Purity | >98% |
Formula | C41H43N3O7S |
Mol Weight | 721.861 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Butler KV, et al. Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A. J Am Chem Soc. 2010 Aug 11;132(31):10842-6.
[2]. Hideshima T, et al. Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8567-72. Epub 2005 Jun 3. [3]. Lu CY, et al. Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis. Int J Mol Sci. 2017 May 1;18(5). |
CoA | CoA of Tubacin |
Smiles: | OCC1=CC=C(C=C1)[C@@H]1C[C@H](CSC2=NC(=C(O2)C2=CC=CC=C2)C2=CC=CC=C2)O[C@@H](O1)C1=CC=C(NC(=O)CCCCCCC(=O)NO)C=C1 |
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