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Product Information:

LUT-014

LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM. LUT014 developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment.

Cat. No.: EX-A2985    Purity: >96%
LUT-014
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg500In-stock
100mg700In-stock
250mg1050In-stock
500mg1450In-stock
1g2250In-stock
5g6600Inquire


CAS No.2274819-46-2
Purity>96%
FormulaC27H19F3N8O
Mol Weight528.488
Appearanceyellow powder
SolubilityDMSO >50 mg/mL; Insoluble in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Noa Shelach. Novel braf inhibitors and use there of for treatment of cutaneous reactions. WO2019026065A2.

CoACoA of LUT-014
Smiles:CC1=C(NC2=NC=CC=C2C2=C3N=CNC3=NC=N2)C2=C(C=C1)C(NC1=CC=CC(OC(F)(F)F)=C1)=NC=C2

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