background


Product Information:

PF429242 dihydrochloride

PF429242 dihydrochloride is a reversible and competitive S1P inhibitor with an IC50 of 175 nM.

Cat. No.: EX-A3396    Purity: >98%
PF429242
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg750In-stock
250mg1185In-stock


SynonymsPF429242
CAS No.2248666-66-0
Purity>98%
FormulaC25H37Cl2N3O2
Mol Weight482.486
AppearanceSolid powder
SolubilityDMSO >50mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Uchida L, et al. Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation. Viruses. 2016 Feb 10;8(2). pii: E46. doi: 10.3390/v8020046.

[2]. Hawkins JL, et al. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals. J Pharmacol Exp Ther. 2008 Sep;326(3):801-8.
CoACoA of PF429242 dihydrochloride
Smiles:O=C(N(CCC1=CC=CC=C1OC)[C@H]2CNCC2)C3=CC=C(CN(CC)CC)C=C3.[H]Cl.[H]Cl

KEYWORDS: buy PF429242 dihydrochloride | PF429242 dihydrochloride supplier | purchase | cost | manufacturer | order | distributor | buy 2248666-66-0 | 2248666-66-0 supplier