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Product Information:

Selpercatinib

Selpercatinib (LOXO-292) is a RET kinase inhibitor.

Cat. No.: EX-A2859    Purity: >99%
Selpercatinib
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg385In-stock
500mg585In-stock
1g885In-stock
5g2150In-stock
10g3475In-stock
25g5860In-stock


SynonymsLOXO-292
CAS No.2152628-33-4
Purity>99%
FormulaC29H31N7O3
Mol Weight525.6015
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Şentürk R, et, al. Quantitative bioanalytical assay for the selective RET inhibitors selpercatinib and pralsetinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Jun 15;1147:122131.

[2]. Steven W. Andrews, et al. Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors. WO2018071447A1.

CoACoA of Selpercatinib
Smiles:COC1=CC=C(CN2C3CC2CN(C3)C2=CC=C(C=N2)C2=CC(OCC(C)(C)O)=CN3N=CC(C#N)=C23)C=N1

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