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Product Information:

GSK656

Ganfeborole hydrochloride (GSK656) is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM.

Cat. No.: EX-A3128    Purity: >98%
GSK656
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg585In-stock
25mg785In-stock
50mg1250In-stock
100mg2050In-stock
200mgGet quoteIn-stock
500mgGet quoteIn-stock


SynonymsGanfeborole hydrochloride
Synonyms 2GSK3036656
CAS No.2131798-13-3
Purity>98%
FormulaC10H14BCl2NO4
Mol Weight293.939
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li X, et al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026.

CoACoA of GSK656
Smiles:OCCOC1=CC=C(Cl)C2=C1B(O)O[C@@H]2CN.[H]Cl

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