PXS-5153A

PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.


Cat. No.: EX-A3216	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	400	In-stock
25mg	550	In-stock
50mg	750	In-stock
100mg	950	In-stock
500mg	1650	inquire
1g	2650	inquire

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CAS No.	2125956-82-1
Purity	>98%
Formula	C20H25Cl2FN4O2S
Mol Weight	475.408
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Schilter H, et al. The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis. J Cell Mol Med. 2018 Dec 9.
CoA	CoA of PXS-5153A

Smiles:	CC(N1C/C(F)=C/CN)=C(C2=CC=CC(S(N(C)C)(=O)=O)=C2)C3=C1C=CC=N3.Cl.Cl


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