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Product Information:

Squarunkin A

Squarunkin A is a UNC119-cargo interaction inhibitor. Squarunkin A selectively inhibits the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A with an IC50 value of 10 nm.

Cat. No.: EX-A3486    Purity: >98%
Squarunkin
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg735In-stock
250mg1285In-stock
500mg1885In-stock
1g2600In-stock
5g8800Inquire


CAS No.2101958-02-3
Purity>98%
FormulaC25H32F3N5O4
Mol Weight523.5479
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Mejuch T, Garivet G, Hofer W, Kaiser N, Fansa EK, Ehrt C, Koch O, Baumann M, Ziegler S, Wittinghofer A, Waldmann H. Small-Molecule Inhibition of the UNC119-Cargo Interaction. Angew Chem Int Ed Engl. 2017 May 22;56(22):6181-6186. doi:10.1002/anie.201701905. Epub 2017 May 4. PubMed PMID: 28471079.
CoACoA of Squarunkin A
Smiles:CCOC(=O)N1CCC(CC1)NC2=C(C(=O)C2=O)NCCN3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F

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