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Product Information:

BAY-299

BAY-299 is a very potent, dual inhibitor with IC50s of 67 nM for BRPF2 bromodomains (BD), 8 nM for TAF1 BD2, and 106 nM for TAF1L BD2.

Cat. No.: EX-A2709    Purity: >98%
BAY-299
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg485In-stock
250mg785In-stock
500mg1185In-stock
1g1785In-stock
5g5500In-stock


CAS No.2080306-23-4
Purity>98%
FormulaC25H23N3O4
Mol Weight429.4678
AppearanceLight yellow to yellow solid
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Bouché L, et al. Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains. J Med Chem. 2017 May 11;60(9):4002-4022.

CoACoA of BAY-299
Smiles:CN1C(=O)N(C)C2=CC(N3C(=O)C4=CC=CC5=C4C(=CC=C5CCCO)C3=O)=C(C)C=C12

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