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Product Information:

Salcaprozate sodium

Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation.

Cat. No.: EX-A3434    Purity: 99.98% HPLC; Assay:99.84%
Salcaprozate
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10g550In-stock
25g750In-stock
50g950In-stock
100g1500In-stock


SynonymsSNAC
CAS No.203787-91-1
Purity99.98% HPLC; Assay:99.84%
FormulaC15H20NNaO4
Mol Weight301.3134
Appearancewhite solid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 1 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Riley MGI, et, al. Subchronic oral toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley and Wistar rats. Int J Toxicol. Jul-Aug 2009; 28(4):278-93.

[2]. Twarog C, et, al. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C 10). Pharmaceutics. 2019 Feb 13; 11(2):78.

[3]. Li Y, et, al. Impact of Sodium N-[8-(2-Hydroxybenzoyl)amino]-caprylate on Intestinal Permeability for Notoginsenoside R1 and Salvianolic Acids in Caco-2 Cells Transport and Rat Pharmacokinetics. Molecules. 2018 Nov 16; 23(11):2990.

CoACoA of Salcaprozate sodium
Smiles:C1=CC=C(C(=C1)C(=O)NCCCCCCCC(=O)[O-])O.[Na+]

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