Baloxavir

Baloxavir (Baloxavir acid), derived from the prodrug Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity.


Cat. No.: EX-A2723	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	385	In-stock
250mg	485	In-stock
500mg	750	In-stock
1g	1250	In-stock
5g	2750	In-stock

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Synonyms	Baloxavir acid
Synonyms 2	S-033447
CAS No.	1985605-59-1
Purity	>98%
Formula	C24H19F2N3O4S
Mol Weight	483.487
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Omoto S, et al. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep. 2018 Jun 25;8(1):9633. [2]. Noshi T, et al. In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antiviral Res. 2018 Dec;160:109-117.
CoA	CoA of Baloxavir

Smiles:	[H][C@@]12COCCN1C(=O)C1=C(O)C(=O)C=CN1N2[C@@H]1C2=CC=CC=C2SCC2=C(F)C(F)=CC=C12


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