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Product Information:

PI3K/mTOR Inhibitor-2

PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR.

Cat. No.: EX-A3121    Purity: >98%
PI3K/mTOR
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg600In-stock
50mg850In-stock
100mg1250In-stock
250mg1850In-stock
500mg2650In-stock
1g3985In-stock


SynonymsPI3K/mTOR Inhibitor-2
CAS No.1848242-58-9
Purity>98%
FormulaC20H13ClF2N4O4S
Mol Weight478.856
Appearancesolid powder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yu T, et al. Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR. ACS Med Chem Lett. 2018 Feb 27;9(3):256-261.

CoACoA of PI3K/mTOR Inhibitor-2
Smiles:FC1=CC(F)=C(S(=O)(NC2=CC(C(C=C3)=CN4C3=NC=C(Cl)C4=O)=CN=C2OC)=O)C=C1

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