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Product Information:

SRI 31215 TFA

SRI 31215 TFA, a triplex inhibitor of matriptase, hepsin and hepatocyte growth factor activator (HGFA) with IC50s of 0.69 μM, 0.65 μM, 0.3 μM, blocks pro-HGF activation and thus mimics the activity of HAI-1/2.

Cat. No.: EX-A3201    Purity: >98%
SRI
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg480In-stock
100mg780In-stock
250mg1280In-stock
1g2650In-stock
5gGet quoteinquire


SynonymsSRI 31215 (TFA)
CAS No.1832686-44-8
Purity>98%
FormulaC27H34F3N5O3
Mol Weight533.5858
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Owusu BY, et al. Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling. Oncotarget. 2016 May 17;7(20):29492-506.
CoACoA of SRI 31215 TFA
Smiles:N=C(C1=CC=CC(N2CC(C)CN(CC3CCN(CC4=CC=CC=C4)CC3)C2=O)=C1)N.OC(C(F)(F)F)=O

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