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Product Information:

MLT-748

MLT-748 is a potent, selective and allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM.

Cat. No.: EX-A3344    Purity: >98%
MLT-748
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg990In-stock


CAS No.1832578-30-9
Purity>98%
FormulaC19H19Cl2N9O3
Mol Weight492.319
AppearanceSolid powder
SolubilityDMSO >200 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Quancard J, et al. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat Chem Biol. 2019 Mar;15(3):304-313.
CoACoA of MLT-748
Smiles:O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C([C@@H](OC)[C@H](OC)C)N4C(N=C3)=CC(Cl)=N4

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