dBET1

dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.


Cat. No.: EX-A1817	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	695	In-stock
250mg	950	In-stock
500mg	1250	In-stock
1g	1850	In-stock
5g	5500	In-stock
10g	9200	inquire

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


CAS No.	1799711-21-9
Purity	>98%
Formula	C38H37ClN8O7S
Mol Weight	785.268
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Winter GE, et al. DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation. Science. 2015 Jun 19;348(6241):1376-81.
CoA	CoA of dBET1

Smiles:	CC1=NN=C2[C@H](CC(=O)NCCCCNC(=O)COC3=CC=CC4=C3C(=O)N(C3CCC(=O)NC3=O)C4=O)N=C(C3=C(SC(C)=C3C)N12)C1=CC=C(Cl)C=C1


		Search