KO-947

KO-947 is a potent and selective inhibitor of ERK1/2 kinases. KO-947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling at low nanomolar concentrations.


Cat. No.: EX-A1980	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	750	In-stock
250mg	1200	In-stock
500mg	1800	In-stock

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CAS No.	1695533-89-1
Purity	>98%
Formula	C21H17N5O
Mol Weight	355.3926
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Francis Burrows, et al. KO-947, a potent ERK inhibitor with robust preclinical single agent activity in MAPK pathway dysregulated tumors. Cancer Res 2017;77(13 Suppl):Abstract nr 5168.
CoA	CoA of KO-947

Smiles:	O=C1N=C2C=C3NNC(=C3C=C2CN1CC1=CC=CC=C1)C1=CC=NC=C1


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