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Product Information:

GLPG1837

GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.

Cat. No.: EX-A1819    Purity: >98%
GLPG1837
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg490In-stock
250mg690In-stock
500mg990In-stock
1g1550In-stock


SynonymsABBV-974
CAS No.1654725-02-6
Purity>98%
FormulaC16H20N4O3S
Mol Weight348.42
Appearanceoff-white solid powder
SolubilityDMSO >100mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Van der Plas SE, et al. J Med Chem. 2018 Feb 22;61(4):1425-1435.
CoACoA of GLPG1837
Smiles:CC1(C)CC2=C(SC(NC(=O)C3=CC=NN3)=C2C(N)=O)C(C)(C)O1

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