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Product Information:

Enasidenib mesylate

Enasidenib (AG-221; CC-90007) is a potent and selective IDH2 (Isocitrate dehydrogenase 2) inhibitor with potential anticancer activity.

Cat. No.: EX-A1972    Purity: >98%
Enasidenib
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg490In-stock
250mg770In-stock
500mg1100In-stock
1g1700In-stock


SynonymsAG-221
Synonyms 2CC-90007
CAS No.1650550-25-6
Purity>98%
FormulaC20H21F6N7O4S
Mol Weight569.481
Appearancewhite to off-white powder
SolubilitySoluble in DMSO(>50 mg/mL), not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Alan H. Shih, et al. AG-221, a Small Molecule Mutant IDH2 Inhibitor, Remodels the Epigenetic State of IDH2-Mutant Cells and Induces Alterations in Self-Renewal/Differentiation in IDH2-Mutant AML Model in Vivo. Blood 2014 124:437.
CoACoA of Enasidenib mesylate
Smiles:CS(O)(=O)=O.CC(C)(O)CNC1=NC(=NC(NC2=CC(=NC=C2)C(F)(F)F)=N1)C1=NC(=CC=C1)C(F)(F)F

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