Synonyms | Mavacamten |
---|
Synonyms 2 | SAR439152 |
---|
CAS No. | 1642288-47-8 |
---|
Purity | >98% |
---|
Formula | C15H19N3O2 |
---|
Mol Weight | 273.3303 |
---|
Appearance | solid powder |
---|
Solubility | Soluble in DMSO, not in water |
---|
Shelf Life | >2 years if stored properly |
---|
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
---|
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
---|
|
---|
| |
---|
Reference: | [1]. Kawas RF, et al. A small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle. J Biol Chem. 2017 Oct 6;292(40):16571-16577.
[2]. Stern JA, et al. A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy. PLoS One. 2016 Dec 14;11(12):e0168407.
[3]. Green EM, et al. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 5;351(6273):617-21. |
---|
CoA | CoA of MYK-461 |
---|