background


Product Information:

GNE131

GNE-131 is a potent and selective inhibitor of human sodium channel NaV1.7, with an IC50 of 3 nM.

Cat. No.: EX-A1903    Purity: >98%
GNE131
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder


SynonymsGNE-131
CAS No.1629063-81-5
Purity>98%
FormulaC23H30N4O3S
Mol Weight442.574
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Focken T, et al. Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain. J Med Chem. 2018 Jun 14

CoACoA of GNE131
Smiles:O=S(=O)(NC1=NN=C2C=C(OCC34CC5CC(CC(C5)C3)C4)C(=CN12)C1CC1)C1CC1

KEYWORDS: buy GNE131 | GNE131 supplier | purchase | cost | manufacturer | order | distributor | buy 1629063-81-5 | 1629063-81-5 supplier