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Product Information:

IDH-305

IDH-305 (Compound 13) is an orally available, mutant-selective and brain-penetrant inhibitor of isocitrate dehydrogenase 1 (IDH1).

Cat. No.: EX-A3224    Purity: >98%
IDH-305
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg865In-stock
100mg1450In-stock
250mg2500In-stock
500mg4300In-stock
1g6985In-stock
5g26800In-stock


SynonymsIDH305
CAS No.1628805-46-8
Purity>98%
FormulaC23H22F4N6O2
Mol Weight490.4534
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Young Shin Cho, et al. Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor. ACS Med Chem Lett. 2017 Sep 18;8(10):1116-1121.
CoACoA of IDH-305
Smiles:O=C1OC[C@H]([C@@H](F)C)N1C2=NC(N[C@H](C3=CC(C)=C(C4=CC(C(F)(F)F)=NC=C4)C=N3)C)=NC=C2

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