Zoliflodacin

Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL.


Cat. No.: EX-A2620	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	885	In-stock
100mg	1285	In-stock
200mg	2085	In-stock
500mg	3085	In-stock
1g	Get quote	In-stock

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Synonyms	AZD0914
Synonyms 2	ETX0914
CAS No.	1620458-09-4
Purity	>98%
Formula	C22H22FN5O7
Mol Weight	487.4378
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Huband MD, et al. In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria. Antimicrob Agents Chemother. 2015 Jan;59(1):467-74.
CoA	CoA of Zoliflodacin

Smiles:	[H][C@]12[C@H](C)O[C@H](C)CN1C1=C(CC22C(=O)NC(=O)NC2=O)C=C2C(=NOC2=C1F)N1[C@@H](C)COC1=O


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