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Product Information:

Resiquimod

Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.

Cat. No.: EX-A1879    Purity: >98%
Resiquimod
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg450In-stock
1g685In-stock
5g1485In-stock
10g2485In-stock
25g4885In-stock
50g7885In-stock


SynonymsR-848
Synonyms 2S28463
CAS No.144875-48-9
Purity>98%
FormulaC17H22N4O2
Mol Weight314.3822
Appearancesolid powder
SolubilitySoluble in DMSO, DMF
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33(36):4526-32.

[2]. Brugnolo F, et al. The novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-gamma-producing cells. J Allergy Clin Immunol. 2003 Feb;111(2):380-8.

[3]. Zhou ZX, et al. Immune effects of R848: evidences that suggest an essential role of TLR7/8-induced, Myd88- and NF-κB-dependent signaling in the antiviral immunity of Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2015 Mar;49(1):113-20.
CoACoA of Resiquimod
Smiles:CCOCC1=NC2=C(N1CC(C)(C)O)C1=CC=CC=C1N=C2N

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