ND-630

ND-630 (Firsocostat; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor which inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.


Cat. No.: EX-A2586	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	450	In-stock
250mg	650	In-stock
500mg	850	In-stock
1g	1400	In-stock
5g	4985	In-stock
10g	7850	In-stock

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Synonyms	Firsocostat
Synonyms 2	GS-0976
CAS No.	1434635-54-7
Purity	>98%
Formula	C28H31N3O8S
Mol Weight	569.626
Appearance	white to off-white powder
Solubility	DMSO >50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Harriman G, et al. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1796-805.
CoA	CoA of ND-630

Smiles:	COC1=C(C=CC=C1)[C@H](CN1C2=C(C(C)=C(S2)C2=NC=CO2)C(=O)N(C1=O)C(C)(C)C(O)=O)OC1CCOCC1


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