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Product Information:

FRAX1036

FRAX-1036 is a potent and selective PAK inhibitor with biochemical potency (Ki) of 23.3 nM and 72.4 nM against PAK1 and PAK2.

Cat. No.: EX-A2370    Purity: >98%
FRAX1036
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg550In-stock
250mg800In-stock
500mg1100In-stock
1g1550In-stock
5g4650In-stock
10g7440In-stock


CAS No.1432908-05-8
Purity>98%
FormulaC28H32ClN7O
Mol Weight518.053
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ong CC, et al. Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents. Breast Cancer Res. 2015 Apr 23;17:59.

[2]. Mortazavi F, et al. Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis. BMC Cancer. 2015 May 9;15:381.

CoACoA of FRAX1036
Smiles:CCN1C(=O)C(=CC2=CN=C(NCCC3CCN(C)CC3)N=C12)C1=CC=C(C=C1Cl)C1=NC(C)=CN=C1

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