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Product Information:

EI1

EI1 is a potent EZH2 inhibitor that has activity against both wild-type and Y641F mutant EZH2 (IC₅₀s = 15 and 13 nM, respectively).

Cat. No.: EX-A2431    Purity: >98%
EI1
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
200mg735In-stock
500mg985In-stock
1g1385In-stock
5g3950In-stock
10g5900In-stock


SynonymsEzh2 Inhibitor II
CAS No.1418308-27-6
Purity>98%
FormulaC23H26N4O2
Mol Weight390.4781
Appearancewhite solid
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Qia W, Chan HM, Teng L, Li L, Chuai S, Zhang RP, Zeng J, Li M, Fan H, Lin Y, Gu J, Ardayfiob O, Zhang JH, Yan X, Fang J, Mi Y, Zhang M, Zhou T, Feng G, Chen ZJ, Li G, Yang T, Zhao K, Liu X, Yu Z, Lu CX, Atadja P and Li E. Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation. Proc Natl Acad Sci. 2012 Dec; 109(52): 213605.
CoACoA of EI1
Smiles:CCC(CC)N1C=CC2=C1C=C(C=C2C(=O)NCC1=C(C)C=C(C)NC1=O)C#N

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