GC-376

GC376 (GC-376) is a broad-spectrum antiviral agent that inhibits 3C or 3C-like proteases (3Cpro or 3CLpro) of picornaviruses, noroviruses, and coronaviruses with IC50 of 0.96 (MD145), 0.82 (TGEV) and 0.2 uM (HRV) in FRET protease assays.


Cat. No.: EX-A3054	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	360	In-stock
1g	530	In-stock
5g	1450	In-stock
10g	2400	In-stock

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Synonyms	GC-376 sodium
CAS No.	1416992-39-6
Purity	>98%
Formula	C21H31N3NaO8S
Mol Weight	508.541
Appearance	Solid powder
Solubility	Soluble in DMSO, not in water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	1. Kim Y, et al. J Virol. 2012 Nov;86(21):11754-62. 2. Takahashi D, et al. Virus Res. 2013 Dec 26;178(2):437-44. 3. Pedersen NC, et al. J Feline Med Surg. 2018 Apr;20(4):378-392.
CoA	CoA of GC-376

Smiles:	CC(C)C[C@@H](C(=O)N[C@@H](CC1CCNC1=O)C(O)S(=O)(=O)O)NC(=O)OCC2=CC=CC=C2.[Na+]


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