GNE-0877

GNE0877 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitor with an IC50 of 3 nM.


Cat. No.: EX-A2062	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	650	In-stock
250mg	950	In-stock
500mg	1350	In-stock
1g	1950	In-stock
5g	5600	Inquire

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CAS No.	1374828-69-9
Purity	>98%
Formula	C14H16F3N7
Mol Weight	339.3189
Appearance	solid powder
Solubility	Soluble in DMSO,>100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Estrada AA, et al. Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. J Med Chem. 2014 Feb 13;57(3):921-36.
CoA	CoA of GNE-0877

Smiles:	CNC1=NC(NC2=CN(N=C2C)C(C)(C)C#N)=NC=C1C(F)(F)F


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