Val-Ala-PAB

Val-Ala-PAB is a building block in the synthesis of Tesirine (a.k.a. SG3249), a clinical antibody-drug conjugate pyrrolobenzodiazepine dimer payload. Reagent in the preparation of pyrrolobenzodiazepine dimers and their antibody conjugates containing peptide linkers useful for treating proliferative including cancer.


Cat. No.: EX-A2603	Purity: >98%

For research only, Do not use for Human!

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CAS No.	1343476-44-7
Purity	>98%
Formula	C15H23N3O3
Mol Weight	293.3614
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	Dimasi, N., et al.: Mol. Pharm., 14, 1501 (2017); Howard, P. W., et al.: PCT Int. Appl. (2011), WO 2011130598 A1 20111020;
CoA	CoA of Val-Ala-PAB

Smiles:	CC(C)[C@H](N)C(=O)N[C@@H](C)C(=O)NC1=CC=C(CO)C=C1


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