Tyrphostin AG 528

Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively. Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC50s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for ErbB2. Tyrphostin AG 528 is also an anticancer agent.


Cat. No.: EX-A2364	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	500	In-stock
500mg	750	In-stock
1g	1100	In-stock
5g	2850	In-stock
10g	4200	In-stock

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Synonyms	Tyrphostin B66
Synonyms 2	AG 528
CAS No.	133550-49-9
Purity	>98%
Formula	C18H14N2O3
Mol Weight	306.3154

Reference:	[1]. Naijue Zhu, et al. Tyrphostin Tumor Growth Inhibitors of EGFR and ErbB2 Tyrosine Kinase. J Chem Crystallogr. 2007, 37, 679–683. [2]. Sheikhi M, et al. Investigation of Adsorption Tyrphostin AG528 Anticancer Drug Upon the CNT(6,6-6) Nanotube: A DFT Study. Curr Mol Med. 2019;19(2):91-104.
CoA	CoA of Tyrphostin AG 528

Smiles:	OC1=CC=C(\C=C(/C#N)C(=O)N2CCC3=CC=CC=C23)C=C1O


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