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Product Information:

Rimegepant

Rimegepant (BMS-927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.

Cat. No.: EX-A1922    Purity: >98%
Rimegepant
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg400In-stock
250mg600In-stock
500mg950In-stock
1g1750In-stock
5g5800In-stock
10g8600In-stock


SynonymsBMS-927711
CAS No.1289023-67-1
Purity>98%
FormulaC28H28F2N6O3
Mol Weight534.5571
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Luo G, et al. Discovery of (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): an oral calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraine. J Med Chem. 2012 Dec 13;55(23):10644-51.

[2]. Zheng N, et al. Improved liquid-liquid extraction with inter-well volume replacement dilution workflow and its application to quantify BMS-927711 in rat dried blood spots by UHPLC-MS/MS. J Pharm Biomed Anal. 2014 Feb;89:240-50.

CoACoA of Rimegepant
Smiles:N[C@H]1[C@@H](CC[C@@H](OC(=O)N2CCC(CC2)N2C(=O)NC3=C2C=CC=N3)C2=NC=CC=C12)C1=C(F)C(F)=CC=C1

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