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Product Information:

E3 ligase Ligand 5

PROTAC ERRα ligand 1 is an estrogen-related receptor α (ERRα) antagonist with IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively.

Cat. No.: EX-A3298    Purity: >98%
E3
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg685In-stock
250mg1085In-stock
500mg1685In-stock
1g2585In-stock
5gGet quoteIn-stock


SynonymsPROTAC ERRα ligand 1
CAS No.1264754-13-3
Purity>98%
FormulaC19H11F3N2O4S
Mol Weight420.362
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Patch RJ, et al. Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents. J Med Chem. 2011 Feb 10;54(3):788-808.

CoACoA of E3 ligase Ligand 5
Smiles:N#CC1=CC=C(OC2=CC=C(/C=C(SC(N3)=O)/C3=O)C=C2OC)C(C(F)(F)F)=C1

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