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Product Information:

PF-04979064

PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with Kis of 0.13 nM and 1.42 nM for PI3Kα and mTOR, respectively.

Cat. No.: EX-A1855    Purity: >98%
PF-04979064
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg600In-stock
200mg925In-stock
500mg1650In-stock
1g2850In-stock


CAS No.1220699-06-8
Purity>98%
FormulaC24H26N6O3
Mol Weight446.5016
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Komal L. Jhaveri, et al. A first-in-human phase 1a/b trial of LY3484356, an oral selective estrogen receptor (ER) degrader (SERD) in ER+ advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC): Results from the EMBER study. 2021 ASCO Annual Meeting I.

[2]. Cristina Hernando, et al. Oral Selective Estrogen Receptor Degraders (SERDs) as a Novel Breast Cancer Therapy: Present and Future from a Clinical Perspective. Int. J. Mol. Sci. 2021, 22(15), 7812.

CoACoA of PF-04979064
Smiles:C[C@H](O)C(=O)N1CCC(CC1)N1C(=O)N(C)C2=C1C1=NC(=CC=C1N=C2)C1=CC=C(C)N=C1

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