Product Information:

VU0155069

VU0155069 is a potent and specific inhibitor of PC-PLD1 (phospholipase D1). VU0155069 significantly decreases invasive migration in breast cancer cell lines (MDA-231, 4T1 and PMT). VU0155069 is an inhibitor of PC-PLD2.


Cat. No.: EX-A2008	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	600	In-stock
100mg	900	In-stock
200mg	1250	In-stock
500mg	1950	In-stock
1g	2950	In-stock
5g	8800	Inquire

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


CAS No.	1130067-06-9
Purity	>98%
Formula	C26H28Cl2N4O2
Mol Weight	499.432
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Scott SA, Selvy PE, Buck JR, Cho HP, Criswell TL, Thomas AL, Armstrong MD, Arteaga CL, Lindsley CW, Brown HA. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol. 2009 Feb;5(2):108-17. doi: 10.1038/nchembio.140. Epub 2009 Jan 11. PMID: 19136975; PMCID: PMC3798018.. [2]. Tsai YR, Huang LJ, Lin HY, Hung YJ, Lee MR, Kuo SC, Hsu MF, Wang JP. Inhibition of formyl peptide-stimulated phospholipase D activation by Fal-002-2 via blockade of the Arf6, RhoA and protein kinase C signaling pathways in rat neutrophils. Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun;386(6):507-19. doi: 10.1007/s00210-013-0851-6. Epub 2013 Mar 23. PMID: 23525454. [3]. Kang DW, Park MK, Oh HJ, Lee DG, Park SH, Choi KY, Cho ML, Min do S. Phospholipase D1 has a pivotal role in interleukin-1β-driven chronic autoimmune arthritis through regulation of NF-κB, hypoxia-inducible factor 1α, and FoxO3a. Mol Cell Biol. 2013 Jul;33(14):2760-72. doi: 10.1128/MCB.01519-12. Epub 2013 May 20. PMID: 23689131; PMCID: PMC3700130.
CoA	CoA of VU0155069

Smiles:	Cl.C[C@@H](CN1CCC(CC1)N1C(=O)NC2=C1C=CC(Cl)=C2)NC(=O)C1=CC2=CC=CC=C2C=C1


		Search