SAR125844

SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays.


Cat. No.: EX-A2198	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	485	In-stock
100mg	785	In-stock
250mg	1085	In-stock
1g	1785	In-stock
5g	5355	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


CAS No.	1116743-46-4
Purity	>98%
Formula	C25H23FN8O2S2
Mol Weight	550.631
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Egile C, et al. The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET-amplified cancer. Mol Cancer Ther. 2015 Feb;14(2):384-94.
CoA	CoA of SAR125844

Smiles:	FC1=CC=C(C=C1)C1=NN2C(SC3=CC4=C(C=C3)N=C(NC(=O)NCCN3CCOCC3)S4)=NN=C2C=C1


		Search