LY2562175

LY2562175 is a potent and selective farnesoid X receptor (FXR) agonist. LY2562175 promotes transcriptional activation of human FXR in a cell-based cotransfection assay with EC50 of 193 nM.


Cat. No.: EX-A2794	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	850	In-stock
250mg	1250	In-stock
500mg	1850	In-stock
1g	2650	In-stock
5g	8850	In-stock

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CAS No.	1103500-20-4
Purity	>98%
Formula	C28H27Cl2N3O4
Mol Weight	540.438
Appearance	solid powder
Solubility	DMF: 20 mg/ml DMSO: 30 mg/ml DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Genin MJ, et al. Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia. J Med Chem. 2015 Dec 24;58(24):9768-72.
CoA	CoA of LY2562175

Smiles:	CN1C=C(C(O)=O)C2=C1C=C(C=C2)N1CCC(CC1)OCC1=C(ON=C1C1=C(Cl)C=CC=C1Cl)C1CC1


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