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Product Information:

LY2510924

LY2510924 is a potent and selective CXCR4 antagonist that blocks SDF-1 binding to CXCR4 with an IC50 of 0.079 nM.

Cat. No.: EX-A1847    Purity: >98%
LY2510924
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg875In-stock
200mg1350In-stock


CAS No.1088715-84-7
Purity>98%
FormulaC62H88N14O10
Mol Weight1189.45
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Peng SB, et al. Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models. Mol Cancer Ther. 2015 Feb;14(2):480-90.

[2]. Cho BS, et al. Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy. Blood. 2015 Jul 9;126(2):222-32.
CoACoA of LY2510924
Smiles:CC(C)NCCCC[C@H](NC(=O)[C@H]1CCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@H](CC2=CC=C(O)C=C2)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N[C@H](CCC\N=C(/N)N)C(=O)N[C@@H](CC2=CC3=CC=CC=C3C=C2)C(=O)NCC(=O)N1)C(N)=O

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