Finerenone

Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM.


Cat. No.: EX-A2845	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	485	In-stock
250mg	785	In-stock
500mg	1185	In-stock
1g	1685	In-stock
5g	5350	In-stock
10g	7650	In-stock

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Synonyms	BAY 94-8862
CAS No.	1050477-31-0
Purity	>98%
Formula	C21H22N4O3
Mol Weight	378.4244
Appearance	solid powder
Solubility	Soluble in DMSO, Ethanol
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Raquel González-Blázquez, et al. Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress. Front Pharmacol. 2018 Oct 9;9:1131. [2]. Jochen Dutzmann, et al. The novel mineralocorticoid receptor antagonist finerenone attenuates neointima formation after vascular injury. PLoS One. 2017 Sep 19;12(9):e0184888.
CoA	CoA of Finerenone

Smiles:	CCOC1=NC=C(C)C2=C1[C@H](C1=C(OC)C=C(C=C1)C#N)C(C(N)=O)=C(C)N2


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