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Product Information:

SB 706504

SB 706504 is a potent p38 MAPK inhibitor that inhibits Lipopolysaccharides stimulated inflammatory gene expression in macrophages in chronic obstructive pulmonary disease (COPD)[1].

Cat. No.: EX-A14384    Purity: >98%
Chemical
Chemical structure of SB 706504


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg830In-stock
250mg1650In-stock
500mg2620In-stock
1g4100In-stock


CAS No.911110-38-8
Purity>98%
FormulaC24H19F3N8O
Mol Weight492.4559
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lauren M. Kent, et al. Inhibition of lipopolysaccharide-stimulated chronic obstructive pulmonary disease macrophage inflammatory gene expression by dexamethasone and the p38 mitogen-activated protein kinase inhibitor N-cyano-N'-(2-{[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7-oxo-7,8-dihydropyrido[2,3-d] pyrimidin-2-yl]amino}ethyl)guanidine (SB706504).

CoACoA of SB 706504
Smiles:CC1=C(C=CC(=C1)F)C2=C3C=CC(=O)N(C3=NC(=N2)NCCN=C(N)NC#N)C4=C(C=CC=C4F)F

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