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Product Information:

SB-204990

SB 204990 is a potent and specific inhibitor of ATP citrate lyase (ACLY) enzyme.

Cat. No.: EX-A6876A    Purity: >98%
Chemical
Chemical structure of SB-204990


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg479in_stock
100mg693in_stock
250mg1226in_stock
500mg2076in_stock
1g3338in_stock


CAS No.154566-12-8
Purity>98%
FormulaC18H22Cl2O5
Mol Weight389.27
ColorWhite to off-white
Statesolid
SolubilityDMSO : ? 100 mg/mL H2O : 25 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Shares BH, et al. Active mitochondria support osteogenic differentiation by stimulating β-catenin acetylation. J Biol Chem. 2018 Oct 12;293(41):16019-16027.

[2]. Pearce NJ, et al. The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076. Biochem J. 1998 Aug 15;334 ( Pt 1):113-9.

CoACoA of SB-204990
Smiles:C(C(O)=O)[C@@]1(O)C[C@@H](CCCCCCC2=C(Cl)C=C(Cl)C=C2)OC1=O

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