SAR 444727

Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling .


Cat. No.: EX-A8599	Purity: >98%

	Chemical structure of SAR 444727

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	779	in_stock
500mg	1294	in_stock
1g	2049	in_stock
2g	2991	in_stock
5g	5211	in_stock

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


Synonyms	Atuzabrutinib
Synonyms 2	PRN473
CAS No.	1581714-49-9
Purity	>98%
Formula	C30H30FN7O2
Mol Weight	539.6033
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	4°C, sealed storage, away from moisture and light
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Herter JM, et al. PRN473, an inhibitor of Bruton's tyrosine kinase, inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling. Br J Pharmacol. 2018;175(3):429-439.
CoA	CoA of SAR 444727

Smiles:	NC1=C2C(N([C@H]3CN(CCC3)C(/C(C#N)=C/C(C)(C)C)=O)N=C2C4=C(C=C(C=C4)OC5=CC=CC=C5)F)=NC=N1


		Search