S2-16

S2-16 is a synthetic peptide from the S2 region of cardiac myosin. S2-16 is a cryptic epitope that induces myocarditis in Lewis rats. A cryptic epitope is an epitope that is not recognized by antibodies or T cells after the animal is immunized with the intact antigen. S2-16 can be used to study the mechanism of autoimmune myocarditis .


Cat. No.: EX-A9746	Purity: >98%

	Chemical structure of S2-16

For research only, Do not use for Human!

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CAS No.	672333-56-1
Purity	>98%
Formula	C126H218N36O44S
Mol Weight	2973.359
Color	White to off-white
State	Solid
Solubility	Soluble in H2O
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture, 1 year; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Cryptic Epitope Identified in Rat and Human Cardiac Myosin S2 Region Induces Myocarditis in the Lewis Rat By: Li, Ya; Heuser, Janet S.; Kosanke, Stanley D.; Hemric, Mark; Cunningham, Madeleine W. Journal of Immunology (2004), 172(5), 3225-3234 \| Language: English, Database: CAplus and MEDLINE [1].Protection against experimental autoimmune myocarditis is mediated by interleukin-10-producing T cells that are controlled by dendritic cells By: Li, Ya; Heuser, Janet S.; Kosanke, Stanley D.; Hemric, Mark; Cunningham, Madeleine W. American Journal of Pathology (2005), 167(1), 5-15 \| Language: English, Database: CAplus and MEDLINE
CoA	CoA of S2-16

Smiles:	CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O


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