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Product Information:

(S)-Willardiine

(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM.

Cat. No.: EX-A15634    Purity: >98%
Chemical
Chemical structure of (S)-Willardiine


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg1482Inquire


Synonyms(-)-Willardiine
CAS No.21416-43-3
Purity>98%
FormulaC7H9N3O4
Mol Weight199.1641
ColorWhite to off-white
StateSolid
Solubilitysoluble in H2O
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Patneau DK, et al. Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine. J Neurosci. 1992 Feb;12(2):595-606.

[2]. Fukushima T, et al. Calcium inhibits willardiine-induced responses in kainate receptor GluR6(Q)/KA-2. Neuroreport. 2001 Jan 22;12(1):163-7.

[3]. Gressens P, et al. The effects of AMPA receptor antagonists in models of stroke and neurodegeneration. Eur J Pharmacol. 2005 Sep 5;519(1-2):58-67.

CoACoA of (S)-Willardiine
Smiles:N[C@@H](CN(C(N1)=O)C=CC1=O)C(O)=O

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