(S,S)-PLX-4545

(S,S)-PLX-4545 (Compound I) is an orally active and cereblon-based molecular glue degrader of IKZF2 (zinc finger transcription factor Helios). (S,S)-PLX-4545 can be used for the study of IKZF2-mediated diseases or disorders, such as proliferative diseases or disorders and/or cancer .


Cat. No.: EX-A16285	Purity: >98%

	Chemical structure of (S,S)-PLX-4545

For research only, Do not use for Human!

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1g	get quote	inquire

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CAS No.	2892065-49-3
Purity	>98%
Formula	C28H31N3O4
Mol Weight	473.5634
State	solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Pengyu YANG, et al. Salts and solid forms of compounds that modulate ikzf2. WO2025024823A1.
CoA	CoA of (S,S)-PLX-4545

Smiles:	O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=CC(O[C@H]4CCCC[C@@H]4N5CC(C5)C6=CC=CC=C6)=C3


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