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Product Information:

(S)-B-973B

(-)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity.

Cat. No.: EX-A2780    Purity: >98%
Chemical
Chemical structure of (S)-B-973B


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg780In-stock
100mg980In-stock
200mg1585In-stock


Synonyms(-)-(S)-B-973B
CAS No.2244989-34-0
Purity>98%
FormulaC24H26F2N6O
Mol Weight452.4996
Coloryellowish
Statepowder
SolubilityDMSO >50mg/mL; Insoluble in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Garai S, et al. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.
CoACoA of (S)-B-973B
Smiles:C[C@H](NC(=O)CCC1=CC(F)=C(F)C=C1)C1=CN=CC(=N1)N1CCN(CC1)C1=NC=CC=C1

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