S-Amisulpride

(S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.


Cat. No.: EX-A5710	Purity: >98%

	Chemical structure of S-Amisulpride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	568	in_stock
500mg	755	in_stock
1g	1098	in_stock

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Synonyms	Esamisulpride
Synonyms 2	4199-09-01 00:00:00
CAS No.	71675-92-8
Purity	>98%
Formula	C17H27N3O4S
Mol Weight	369.479
Color	White to light yellow
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Timothy J Donahue, et al. (S)-amisulpride as a discriminative stimulus in C57BL/6 mice and its comparison to the stimulus effects of typical and atypical antipsychotics. Eur J Pharmacol. 2014 Jul 5;734:15-22. [2]. Vincent Grattan, et al. Antipsychotic Benzamides Amisulpride and LB-102 Display Polypharmacy as Racemates, S Enantiomers Engage Receptors D₂ and D₃, while R Enantiomers Engage 5-HT₇. ACS Omega. 2019 Aug 15;4(9):14151-14154.
CoA	CoA of S-Amisulpride

Smiles:	CCN1CCC[C@H]1CNC(C2=CC(S(=O)(CC)=O)=C(N)C=C2OC)=O


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