(S)-ACE-OH

(S)-ACE-OH is a molecular glue with anticancer activity. (S)-ACE-OH promotes nucleoporin degradation and disruption of nucleocytoplasmic trafficking by inducing the interaction between E3 ubiquitin ligase TRIM21 and nucleoporin NUP98 .


Cat. No.: EX-A15121	Purity: >98%

	Chemical structure of (S)-ACE-OH

For research only, Do not use for Human!

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Purity	>98%
Formula	C19H24N2OS
Mol Weight	328.472

Reference:	[1]. Lu P, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders[J]. Cell, 2024.
CoA	CoA of (S)-ACE-OH

Smiles:	C[C@@H](C1=CC2=C(SC3=C(N2CCCN(C)C)C=CC=C3)C=C1)O


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