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Product Information:

S-63845

S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1.

Cat. No.: EX-A1632    Purity: >98%
Chemical
Chemical structure of S-63845


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg521in_stock
100mg875in_stock
250mg1819in_stock
500mg3171in_stock
1g5093in_stock


CAS No.1799633-27-4
Purity>98%
FormulaC39H37ClF4N6O6S
Mol Weight829.259
Colorwhite to off-white
Statepowder
SolubilityDMSO > 50mg/mL, Insoluble in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Kotschy A, et al. The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models. Nature. 2016 Oct 27;538(7626):477-482.
CoACoA of S-63845
Smiles:CN1CCN(CCOC2=C(Cl)C(C)=C(C=C2)C2=C(SC3=NC=NC(O[C@H](CC4=C(OCC5=CC=NN5CC(F)(F)F)C=CC=C4)C(O)=O)=C23)C2=CC=C(F)O2)CC1

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